Caution: Before you attempt these tweaks, please make sure that you have a backup of your registry, just incase something goes wrong in the middle.
Locking Folders:
* Consider you want to lock a folder named XXXX in your E:\, whose path is E:\XXXX.
* Now open the Notepad and type the following
ren xxxx xxxx.{21EC2020-3AEA-1069-A2DD-08002B30309D}
* Where xxxx is your folder name. Save the text file as loc.bat in the same drive.
* Open another new notepad text file and type the following
ren xxxx.{21EC2020-3AEA-1069-A2DD-08002B30309D} xxxx
* Save the text file as key.bat in the same drive.
Steps to lock the folder:
* To lock the xxxx folder, simply click the loc.bat and it will transform into control panel icon which is inaccessible.
* To unlock the folder click the key.bat file. Thus the folder will be unlocked and the contents are accessible.